Immunology and Cancer Biology University of California

New advances in invasive aspergillosis immunobiology main the best way in the direction of personalised therapeutic approaches

Invasive aspergillosis (IA) stays a devastating illness in immune compromised sufferers regardless of important advances in our understanding of fungal virulence and host protection mechanisms. On this evaluate, we summarize vital analysis advances within the battle towards IA with explicit concentrate on early occasions within the interactions between Aspergillus fumigatus and the host that happen within the respiratory tract.

 

Advances in understanding mechanisms of immune effector cell recruitment, antifungal effector mechanisms, and the way the dynamic host-fungal interplay alters the native microenvironment to impact outcomes are highlighted.

 

These advances illustrate thrilling new therapeutic alternatives, but in addition emphasize the significance of understanding every distinctive fungus-host interplay for enhancing affected person outcomes.

The Immunobiology and medical options of kind 1 autoimmune polyglandular syndrome (APS-1)

Autoimmune Polyglandular Syndrome kind 1 (APS-1) is a subtype of the autoimmune polyendocrine syndrome characterised by the simultaneous or sequential dysfunction of a number of endocrine or non-endocrine glands.

A medical prognosis of APS-1 is often based mostly on the presence of a minimum of two of three following standards: continual mucocutaneous candidiasis, hypoparathyroidism and adrenal insufficiency.

The primary recognized causative mutated gene for APS-1 is autoimmune regulator (AIRE) encoding a important transcription issue, which is primarily expressed within the medullary thymic epithelial cells (mTECs) for producing central immune tolerance. A variety of continual, debilitating issues, with no apparent correlation with genetics, makes a prognosis of APS-1 difficult early within the illness course.

Managing APS-1 is tough resulting from its complexity, particularly the intricate relationships inside manifestations and genetic mutations. The previous a long time have witnessed dramatic progress in elucidating the perform of AIRE and conducting large-scale cohort research in APS-1. Nonetheless, no clear evidence-based pointers have been established in APS-1.

On this evaluate, we offer an in depth important overview of the examine historical past, epidemiology, medical options, and associated mechanisms of autoimmunity in APS-1, in addition to at the moment out there therapies for this autoimmune dysfunction.

Twin requirement for STAT signaling in dendritic cell immunobiology

Dendritic cells (DC) symbolize a horny goal for therapeutic manipulation of the immune system and enhancement of inadequate immune response in most cancers. STAT members of the family play key roles within the differentiation and activation of DC, a function that’s at the moment being exploited in DC-based therapies.

• We beforehand reported that the small-molecule Stattic, initially developed as a STAT3-specific inhibitor, additionally inhibits STAT1 and STAT2 phosphorylation in DC uncovered to cytokines or LPS.
• Purpose of this examine was to analyze the useful penalties of in vitro remedy with Stattic on DC immunobiology. Curiously, we noticed an reverse impact of Stattic on DC immunophenotype relying on the activation state.
• Whereas the expression of costimulatory, coinhibitory, MHC class II and CD83 molecules was enhanced in immature DC uncovered to Stattic, the LPS induced up-modulation of those molecules was strongly repressed.
• An efficient blockade of LPS-induced secretion of proinflammatory cytokines and capability to stimulate a Th1 polarization was additionally noticed within the presence of Stattic. Our outcomes point out that the immunological penalties of STAT inhibition in DC differ relying on the cell activation state.
• This information is of relevance for anticipating potential results of STAT-targeted therapeutics, and pursuing selective DC manipulation in medical purposes.

Immunobiology of Lengthy Noncoding RNAs.

The invention of lengthy noncoding RNAs (lncRNA) has supplied a brand new perspective on gene regulation in various organic contexts. lncRNAs are remarkably versatile molecules that work together with RNA, DNA, or proteins to advertise or restrain the expression of protein-coding genes.

Activation of immune cells is related to dynamic adjustments in expression of genes, the merchandise of which fight infectious microorganisms, provoke restore, and resolve inflammatory responses in cells and tissues.

Latest proof signifies that lncRNAs play vital roles in directing the event of various immune cells and controlling the dynamic transcriptional packages which can be an indicator of immune cell activation.

The significance of those molecules is underscored by their newly acknowledged roles in inflammatory ailments. On this evaluate, we talk about the contribution of lncRNAs within the improvement and activation of immune cells and their roles in immune-related ailments. We additionally talk about challenges confronted in figuring out organic features for this huge and sophisticated class of genes.

Pathobiology and Immunobiology of Acanthamoeba Keratitis: Insights from Animal Fashions

Acanthamoeba keratitis (AK) is a uncommon however sight-threatening illness brought on by pathogenic species of Acanthamoeba. Regardless of its ubiquitous nature, the incidence of AK is comparatively low in comparison with different types of infectious keratitis.

Though contact lens put on is a significant danger issue, publicity to contaminated water and ocular trauma are additionally related to AK. As soon as a affected person develops AK the prognosis could be very poor until an aggressive remedy routine is initiated early.

Among the intriguing options of AK are the shortage of immunological reminiscence, resistance of the dormant cyst kind to remedy, variations between the pathogenic strains and soil isolates of Acanthamoeba and the distinctive function of the innate immune system in controlling this illness.

Understanding the collection of steps concerned within the pathogenesis of the illness and the host immune response towards Acanthamoeba antigens is essential for growing efficient therapeutic methods focusing on the illness.

Intracellular metabolism is central to cell exercise and performance. CD4(+)CD25(+) regulatory T cells (Tregs) that categorical the transcription issue FOXP3 play a pivotal function within the upkeep of immune tolerance to self.

Latest research confirmed that the metabolism and performance of Tregs are influenced considerably by native environmental situations and the supply of sure metabolites. It additionally was reported that outlined metabolic packages affiliate with Treg differentiation, expression of FOXP3, and phenotype stabilization.

This text opinions how metabolism modulates FOXP3 expression and Treg perform, what environmental elements are concerned, and the way metabolic manipulation might alter Treg frequency and performance in physiopathologic situations.

 

K-Ras Activation Assay Kit, Trial Size
STA-400-K-T	Cell Biolabs	5 assays	EUR 483.6
Description: Our Ras Activation Assays use visible agarose beads to selectively precipitate the active form of specific Ras protein of interest. The precipitated small GTPase is then detected by Western blot using a target-specific antibody included in the kit. Assays are available to detect specific isoforms H-Ras, K-Ras, and N-Ras, as well as a Pan-Ras assay that detects all three isoforms.

N-Ras Activation Assay Kit, Trial Size
STA-400-N-T	Cell Biolabs	5 assays	EUR 483.6
Description: Our Ras Activation Assays use visible agarose beads to selectively precipitate the active form of specific Ras protein of interest. The precipitated small GTPase is then detected by Western blot using a target-specific antibody included in the kit. Assays are available to detect specific isoforms H-Ras, K-Ras, and N-Ras, as well as a Pan-Ras assay that detects all three isoforms.

Ral Activation Assay
STA-408	Cell Biolabs	20 assays	EUR 908.4
Description: Our Ral Activation Assay uses visible agarose beads to selectively precipitate the active form of Ral protein. The precipitated small GTPase is then detected by Western blot using a Ral-specific antibody included in the kit.

Ran Activation Assay
STA-409	Cell Biolabs	20 assays	EUR 908.4
Description: Our Ran Activation Assay uses visible agarose beads to selectively precipitate the active form of Ran protein. The precipitated small GTPase is then detected by Western blot using a Ran-specific antibody included in the kit.

Rac1 Activation Assay
STA-401-1	Cell Biolabs	20 assays	EUR 908.4
Description: Our Rac Activation Assays use visible agarose beads to selectively precipitate the active form of Rac1 or Rac2. The precipitated small GTPase is then detected by Western blot using a Rac1- or Rac2-specific antibody included in the kit.

Rac2 Activation Assay
STA-401-2	Cell Biolabs	20 assays	EUR 908.4
Description: Our Rac Activation Assays use visible agarose beads to selectively precipitate the active form of Rac1 or Rac2. The precipitated small GTPase is then detected by Western blot using a Rac1- or Rac2-specific antibody included in the kit.

RhoA Activation Assay
STA-403-A	Cell Biolabs	20 assays	EUR 908.4
Description: Our Rho Activation Assays use visible agarose beads to selectively precipitate the active form of RhoA, RhoB or RhoC. The precipitated small GTPase is then detected by Western blot using a RhoA-, RhoB- or RhoC-specific antibody included in the kit.

RhoB Activation Assay
STA-403-B	Cell Biolabs	20 assays	EUR 908.4
Description: Our Rho Activation Assays use visible agarose beads to selectively precipitate the active form of RhoA, RhoB or RhoC. The precipitated small GTPase is then detected by Western blot using a RhoA-, RhoB- or RhoC-specific antibody included in the kit.

RhoC Activation Assay
STA-403-C	Cell Biolabs	20 assays	EUR 908.4
Description: Our Rho Activation Assays use visible agarose beads to selectively precipitate the active form of RhoA, RhoB or RhoC. The precipitated small GTPase is then detected by Western blot using a RhoA-, RhoB- or RhoC-specific antibody included in the kit.

Arf1 Activation Assay
STA-407-1	Cell Biolabs	20 assays	EUR 908.4
Description: Our Arf Activation Assays use visible agarose beads to selectively precipitate the active form of Arf1 or Arf 6. The precipitated small GTPase is then detected by Western blot using an Arf1- or Arf6-specific antibody included in the kit.

Arf6 Activation Assay
STA-407-6	Cell Biolabs	20 assays	EUR 908.4
Description: Our Arf Activation Assays use visible agarose beads to selectively precipitate the active form of Arf1 or Arf 6. The precipitated small GTPase is then detected by Western blot using an Arf1- or Arf6-specific antibody included in the kit.

Cdc42 Activation Assay
STA-402	Cell Biolabs	20 assays	EUR 908.4
Description: Our Cdc42 Activation Assays use visible agarose beads to selectively precipitate the active form of Cdc42 protein. The precipitated small GTPase is then detected by Western blot using a Cdc42-specific antibody included in the kit.

Rap1 Activation Assay Kit
STA-406-1	Cell Biolabs	20 assays	EUR 908.4
Description: Our Rap Activation Assays use visible agarose beads to selectively precipitate the active form of Rap1 or Rap2. The precipitated small GTPase is then detected by Western blot using a Rap1- or Rap2-specific antibody included in the kit.

Rap2 Activation Assay Kit
STA-406-2	Cell Biolabs	20 assays	EUR 908.4
Description: Our Rap Activation Assays use visible agarose beads to selectively precipitate the active form of Rap1 or Rap2. The precipitated small GTPase is then detected by Western blot using a Rap1- or Rap2-specific antibody included in the kit.

Ral Activation Assay Kit, Trial Size
STA-408-T	Cell Biolabs	5 assays	EUR 483.6
Description: Our Ral Activation Assay uses visible agarose beads to selectively precipitate the active form of Ral protein. The precipitated small GTPase is then detected by Western blot using a Ral-specific antibody included in the kit.

Ran Activation Assay Kit, Trial Size
STA-409-T	Cell Biolabs	5 assays	EUR 483.6
Description: Our Ran Activation Assay uses visible agarose beads to selectively precipitate the active form of Ran protein. The precipitated small GTPase is then detected by Western blot using a Ran-specific antibody included in the kit.

Rac1 Activation Assay Kit, Trial Size
STA-401-1-T	Cell Biolabs	5 assays	EUR 483.6
Description: Our Rac Activation Assays use visible agarose beads to selectively precipitate the active form of Rac1 or Rac2. The precipitated small GTPase is then detected by Western blot using a Rac1- or Rac2-specific antibody included in the kit.

Rac2 Activation Assay Kit, Trial Size
STA-401-2-T	Cell Biolabs	5 assays	EUR 483.6
Description: Our Rac Activation Assays use visible agarose beads to selectively precipitate the active form of Rac1 or Rac2. The precipitated small GTPase is then detected by Western blot using a Rac1- or Rac2-specific antibody included in the kit.

RhoA Activation Assay Kit, Trial Size
STA-403-A-T	Cell Biolabs	5 assays	EUR 483.6
Description: Our Rho Activation Assays use visible agarose beads to selectively precipitate the active form of RhoA, RhoB or RhoC. The precipitated small GTPase is then detected by Western blot using a RhoA-, RhoB- or RhoC-specific antibody included in the kit.

RhoB Activation Assay Kit, Trial Size
STA-403-B-T	Cell Biolabs	5 assays	EUR 483.6
Description: Our Rho Activation Assays use visible agarose beads to selectively precipitate the active form of RhoA, RhoB or RhoC. The precipitated small GTPase is then detected by Western blot using a RhoA-, RhoB- or RhoC-specific antibody included in the kit.

RhoC Activation Assay Kit, Trial Size
STA-403-C-T	Cell Biolabs	5 assays	EUR 483.6
Description: Our Rho Activation Assays use visible agarose beads to selectively precipitate the active form of RhoA, RhoB or RhoC. The precipitated small GTPase is then detected by Western blot using a RhoA-, RhoB- or RhoC-specific antibody included in the kit.

Rap1 Activation Assay Kit, Trial Size
STA-406-1-T	Cell Biolabs	5 assays	EUR 483.6
Description: Our Rap Activation Assays use visible agarose beads to selectively precipitate the active form of Rap1 or Rap2. The precipitated small GTPase is then detected by Western blot using a Rap1- or Rap2-specific antibody included in the kit.

Rap2 Activation Assay Kit, Trial Size
STA-406-2-T	Cell Biolabs	5 assays	EUR 483.6
Description: Our Rap Activation Assays use visible agarose beads to selectively precipitate the active form of Rap1 or Rap2. The precipitated small GTPase is then detected by Western blot using a Rap1- or Rap2-specific antibody included in the kit.

Arf1 Activation Assay Kit, Trial Size
STA-407-1-T	Cell Biolabs	5 assays	EUR 483.6
Description: Our Arf Activation Assays use visible agarose beads to selectively precipitate the active form of Arf1 or Arf 6. The precipitated small GTPase is then detected by Western blot using an Arf1- or Arf6-specific antibody included in the kit.

Arf6 Activation Assay Kit, Trial Size
STA-407-6-T	Cell Biolabs	5 assays	EUR 483.6
Description: Our Arf Activation Assays use visible agarose beads to selectively precipitate the active form of Arf1 or Arf 6. The precipitated small GTPase is then detected by Western blot using an Arf1- or Arf6-specific antibody included in the kit.

Cdc42 Activation Assay Kit, Trial Size
STA-402-T	Cell Biolabs	5 assays	EUR 483.6
Description: Our Cdc42 Activation Assays use visible agarose beads to selectively precipitate the active form of Cdc42 protein. The precipitated small GTPase is then detected by Western blot using a Cdc42-specific antibody included in the kit.

Rac1/Cdc42 Activation Assay Combo Kit
STA-404	Cell Biolabs	2 x 20 assays	EUR 1305.6
Description: Our Rac1/Cdc42 Activation Assays use visible agarose beads to selectively precipitate the active form of the small GTPase. The precipitated small GTPase is then detected by Western blot using a specific antibody included in the kit.

RhoA/Rac1/CDC42 Activation Assay Combo Kit
STA-405	Cell Biolabs	3 x 10 assays	EUR 1305.6
Description: Our RhoA/Rac1/Cdc42 Activation Assays use visible agarose beads to selectively precipitate the active form of the small GTPase. The precipitated small GTPase is then detected by Western blot using a specific antibody included in the kit.

96-Well Ras Activation ELISA Kit (Colorimetric)
STA-440	Cell Biolabs	96 assays	EUR 1082.4
Description: Our 96-Well Ras Activation ELISA Kit uses the Raf1 RBD (Rho binding domain) bound to a 96-well plate to selectively pull down the active form of Ras from purified or endogenous samples. The captured GTP-Ras is then detected by a pan-Ras antibody and HRP-conjugated secondary antibody.

96-Well Ras Activation ELISA Kit (Chemiluminescent)
STA-441	Cell Biolabs	96 assays	EUR 1082.4
Description: Our 96-Well Ras Activation ELISA Kit uses the Raf1 RBD (Rho binding domain) bound to a 96-well plate to selectively pull down the active form of Ras from purified or endogenous samples. The captured GTP-Ras is then detected by a pan-Ras antibody and HRP-conjugated secondary antibody.

CORNING® BIOCOAT™ T-CELL ACTIVATION CONTROL 96 WELL FLAT BOTTOM ASSAY PLATE, INDIVIDUALLY WRAPPED, 5/CASE
354730	CORNING	5/pk	EUR 102
Description: Advanced Cells - DL; BioCoat 96 Well Clear - DL

CORNING® BIOCOAT™ T-CELL ACTIVATION ANTI-MOUSE CD3 96 WELL FLAT BOTTOM ASSAY PLATE, INDIVIDUALLY WRAPPED, 5/CASE
354720	CORNING	5/pk	EUR 576
Description: Advanced Cells - DL; BioCoat 96 Well Clear - DL

CORNING® BIOCOAT™ T-CELL ACTIVATION ANTI-HUMAN CD3 96 WELL FLAT BOTTOM ASSAY PLATE, INDIVIDUALLY WRAPPED, 5/CASE
354725	CORNING	5/pk	EUR 568.8
Description: Advanced Cells - DL; BioCoat 96 Well Clear - DL

Stat3 Activation Inhibitor, SPI
1813-2	Biovision	each	EUR 274.8

CD3 (activation epitope) Antibody
abx139107-01mg	Abbexa	0.1 mg	EUR 460.8

GAL4 Activation Domain Antibody
20-abx330273	Abbexa	EUR 376.80 EUR 292.80	100 ug 50 ug

NF-?B Activation Inhibitor III
C3559-25	ApexBio	25 mg	EUR 548.4
Description: NF-?B Activation Inhibitor III is a NF-?B inhibitor.NF-?B (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex controling transcription of DNA, cytokine production as well as cell survival.

NF-?B Activation Inhibitor III
C3559-5	ApexBio	5 mg	EUR 174
Description: NF-?B Activation Inhibitor III is a NF-?B inhibitor.NF-?B (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex controling transcription of DNA, cytokine production as well as cell survival.

CD11b activation epitope Antibody
abx140366-01mg	Abbexa	0.1 mg	EUR 427.2

CD11b activation epitope Antibody
abx140396-01mg	Abbexa	0.1 mg	EUR 427.2

CD3 (activation epitope) Antibody (PE)
abx139119-01mg	Abbexa	0.1 mg	EUR 577.2

EZAct? Procathepsin Activation Buffer
1030-1	Biovision	each	EUR 183.6

CD3 activation epitope Antibody (APC)
abx140478-01mg	Abbexa	0.1 mg	EUR 577.2

CD11b Activation Epitope Antibody (PE)
abx140359-100tests	Abbexa	100 tests	EUR 577.2

CD3 activation epitope Antibody (FITC)
abx140488-01mg	Abbexa	0.1 mg	EUR 510

anti-Lymphocyte Activation Gene 3
YF-PA12911	Abfrontier	100 ug	EUR 483.6
Description: Rabbit polyclonal to Lymphocyte Activation Gene 3

Lymphocyte Activation Gene 3 Antibody
DF13960	Affbiotech	100ul	EUR 420

Lymphocyte Activation Gene 3 Antibody
DF14459	Affbiotech	100ul	EUR 420

Anti-GAL4 Activation Domain antibody
STJ97427	St John's Laboratory	200 µl	EUR 236.4
Description: Rabbit polyclonal to GAL4 Activation Domain.

Anti-Hu CD11b (activation epitope) PE
1P-172-T025	ExBio	25 tests	EUR 168

Anti-Hu CD11b (activation epitope) PE
1P-172-T100	ExBio	100 tests	EUR 288

Rat Calpain Activation-1 (CAPNA1) Elisa Kit
YLA1388RA-48T	Shanghai YL Biotech	48T	EUR 465

Rat Calpain Activation-1 (CAPNA1) Elisa Kit
YLA1388RA-96T	Shanghai YL Biotech	96T	EUR 600

Rat B Cell Activation Factor ELISA kit
E02B0309-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat B Cell Activation Factor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat B Cell Activation Factor ELISA kit
E02B0309-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Rat B Cell Activation Factor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat B Cell Activation Factor ELISA kit
E02B0309-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Rat B Cell Activation Factor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog B Cell Activation Factor ELISA kit
E08B0309-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine B Cell Activation Factor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog B Cell Activation Factor ELISA kit
E08B0309-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Canine B Cell Activation Factor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog B Cell Activation Factor ELISA kit
E08B0309-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Canine B Cell Activation Factor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig B Cell Activation Factor ELISA kit
E07B0309-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine B Cell Activation Factor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig B Cell Activation Factor ELISA kit
E07B0309-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine B Cell Activation Factor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig B Cell Activation Factor ELISA kit
E07B0309-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine B Cell Activation Factor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Non-T-cell Activation Linker Protein
20-abx260597	Abbexa	EUR 3433.20 EUR 393.60 EUR 276.00	1 mg 25 ug 5 ug

Anti-CD3 epsilon (activation epitope) PE
1P-599-C025	ExBio	0.025 mg	EUR 168

Anti-CD3 epsilon (activation epitope) PE
1P-599-C100	ExBio	0.1 mg	EUR 288

Neutral Sphingomyelinase Activation Associated Factor (NSMAF) Antibody
20-abx173814	Abbexa	EUR 1028.40 EUR 526.80	1 mg 200 ug

Neutral Sphingomyelinase Activation Associated Factor (NSMAF) Antibody
20-abx128336	Abbexa	EUR 510.00 EUR 159.60 EUR 1446.00 EUR 693.60 EUR 393.60	100 ug 10 ug 1 mg 200 ug 50 ug

GAL4 Activation Domain Polyclonal Antibody
ABP57231-003ml	Abbkine	0.03ml	EUR 189.6
Description: A polyclonal antibody for detection of GAL4 Activation Domain from Human. This GAL4 Activation Domain antibody is for WB. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein

GAL4 Activation Domain Polyclonal Antibody
ABP57231-01ml	Abbkine	0.1ml	EUR 346.8
Description: A polyclonal antibody for detection of GAL4 Activation Domain from Human. This GAL4 Activation Domain antibody is for WB. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein

GAL4 Activation Domain Polyclonal Antibody
ABP57231-02ml	Abbkine	0.2ml	EUR 496.8
Description: A polyclonal antibody for detection of GAL4 Activation Domain from Human. This GAL4 Activation Domain antibody is for WB. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein

GAL4 Activation Domain Polyclonal Antibody
ES8230-100ul	ELK Biotech	100ul	EUR 334.8
Description: A Rabbit Polyclonal antibody against GAL4 Activation Domain from . This antibody is tested and validated for WB, ELISA

GAL4 Activation Domain Polyclonal Antibody
ES8230-50ul	ELK Biotech	50ul	EUR 248.4
Description: A Rabbit Polyclonal antibody against GAL4 Activation Domain from . This antibody is tested and validated for WB, ELISA

GAL4 Activation Domain Polyclonal Antibody
EA201-100ul	ELK Biotech	100ul	EUR 334.8
Description: A Rabbit Polyclonal antibody against GAL4 Activation Domain. This antibody is tested and validated for WB, ELISA

GAL4 Activation Domain Polyclonal Antibody
EA201-50ul	ELK Biotech	50ul	EUR 248.4
Description: A Rabbit Polyclonal antibody against GAL4 Activation Domain. This antibody is tested and validated for WB, ELISA

FAP Antibody / Fibroblast activation protein
RQ4022	NSJ Bioreagents	100 ug	EUR 356.15
Description: Fibroblast activation protein alpha is a homodimeric 170 kDa melanoma membrane-bound gelatinase, protein that in humans is encoded by the FAP gene. The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

anti-Fibroblast activation protein, alpha
YF-PA11714	Abfrontier	50 ug	EUR 435.6
Description: Mouse polyclonal to Fibroblast activation protein, alpha

anti-Fibroblast activation protein, alpha
YF-PA11715	Abfrontier	100 ug	EUR 483.6
Description: Rabbit polyclonal to Fibroblast activation protein, alpha

Goat B Cell Activation Factor ELISA kit
E06B0309-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat B Cell Activation Factor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.