The E3/E4 ubiquitin conjugation factor UBE4B interacts with and ubiquitinates the HTLV-1 Tax oncoprotein to promote NF-κB activation

Human T-cell leukemia virus kind 1 (HTLV-1) is the etiological agent of grownup T-cell leukemia/lymphoma (ATLL), and the neurological illness HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP).

by Frank Rivera5 Min Reading